If possible, you should change your media cache so that it is on its own dedicated solid state drive, or at least on a solid state drive that isn’t your operating system’s drive. The default Adobe location will be on your primary drive where your operating system is installed, which can cause slowdowns. You can browse a new location for your media cache. While you’re here, you might want to adjust some of your cache settings. Here are the default locations, but if you’ve changed this location you’ll need to remember where you set it. If you can’t open Premiere Pro, you can manually delete the media cache by navigating to the location. Deleting all media cache files will actually delete all of the files, so select this to clear your cache completely. The first option only deletes files that can no longer be found in projects, so that’s not what we want. Clicking the delete will pop up another window that asks whether you’d like to delete unused media cache files or all media cache files. You’ll see a Remove Media Cache Files button. To delete the cache, open Premiere Pro without opening up a project, then click on Edit, then Preferences, then Media Cache.

Clear cache after effects